发现白癜风怎么办急性颅脑损伤血清P―选择素监测的临床价值
【摘要】 目的:探讨血清P-选择素(P-selectin)在急性颅脑损伤监测中的临床价值。方法:90例急性颅脑损伤患者根据GCS评分分为轻型组(30例)、中型组(30例)和重型组(30例),检测三组发病后第1天血清P-selectin及D-Dimer表达水平。同时选择30例门诊健康体检者作为对照组,检测对照组及急性颅脑损伤患者发病后第1、3及7天时血清P-selectin及D-Dimer表达水平。结果:各组急性颅脑损伤患者血清P-selectin及D-Dimer表达水平均明显高于对照组,且随着临床分型逐渐加重,血清P-selectin及D-Dimer表达水平明显升高;急性颅脑损伤患者发病后第1、3及7天血清P-selectin及D-Dimer表达水平均明显高于对照组,且随着发病日期逐渐延长,血清P-selectin及D-Dimer表达水平明显降低;血清P-selectin表达与D-Dimer表达呈正相关性关系,比较差异均具有统计学意义(P中国论文
【关键词】 急性颅脑损伤; P-选择素; D-二聚体
【Abstract】 Objective:To investigate the clinical value of serum P-selectin in monitor of patients with acute brain thod:90 patients with acute brain injury were divided into light group (30 cases),medium group (30 cases) and severe group (30 cases) according to GCS e expression levels of serum P-selectin and D-Dimer 1 d after onset in the three groups were ile 30 healthy outpatients were selected as control group,the expression levels of serum P-selectin and D-Dimer 1,3,and 7 d after onset in the control group and patients with acute brain injury were sult:The expression levels of serum P-selectin and D-Dimer of patients with acute brain injury were significantly higher than that of the control group (P